Yes, leave-in conditioners can be beneficial for locs. Locs require regular moisturization to prevent dryness and breakage, and leave-in conditioners provide a convenient way to keep the hair hydrated throughout the day. Look for leave-in conditioners that are lightweight and non-greasy, as heavy products can lead to buildup and residue in the locs. Additionally, choose leave-in conditioners that are free from harsh chemicals and contain nourishing ingredients such as natural oils or plant-based extracts to promote healthy locs. Remember to apply the leave-in conditioner sparingly, focusing on the mid-lengths and ends of the locs to avoid weighing them down.