Yes, you can use mandelic acid with azelaic acid. Both of these ingredients are commonly found in skincare products and can be used together to address different skin concerns.

Mandelic acid is an alpha-hydroxy acid (AHA) derived from almonds. It has exfoliating properties and can help improve skin texture, reduce the appearance of fine lines and wrinkles, and even out skin tone. Mandelic acid is also known for its antibacterial properties, making it beneficial for acne-prone skin.

Azelaic acid, on the other hand, is a dicarboxylic acid derived from grains such as wheat, rye, and barley. It has anti-inflammatory and anti-bacterial properties, making it effective in treating acne and rosacea. Azelaic acid also helps to regulate skin cell turnover, reducing hyperpigmentation and improving skin tone.

When used together, mandelic acid and azelaic acid can complement each other's effects on the skin. Mandelic acid can help exfoliate the skin and enhance the penetration of azelaic acid, allowing it to work more effectively. Azelaic acid, in turn, can help calm inflammation and provide additional antibacterial benefits.

However, it is important to note that every individual's skin is unique, and some people may experience sensitivity or irritation when using these acids together. It is always recommended to patch test new products and gradually introduce them into your skincare routine. If you have sensitive skin or are unsure about using these ingredients together, it is best to consult with a dermatologist or skincare professional.