Expired makeup can affect both men and women similarly because the potential risks and adverse effects are more related to the condition of the product and how it interacts with the skin, rather than the gender of the person using it.

When makeup expires, it can undergo chemical changes that may lead to the growth of bacteria and mold. These microorganisms can cause skin irritations, infections, and allergic reactions, regardless of whether the user is male or female.

Moreover, the chemical changes in expired makeup can lead to a decrease in performance and efficacy. For instance, the product may not spread evenly, the pigmentation may change, or it may not provide the same level of coverage or protection.

However, individual skin types and conditions can influence how one's skin reacts to expired makeup. Some people may experience more severe reactions than others, depending on their skin sensitivity, skin type (oily, dry, combination, or normal), and any pre-existing skin conditions.

In conclusion, the adverse effects of using expired makeup are not gender-specific but are more related to the product's condition and the individual's skin type and condition. Therefore, it is always recommended to check the expiration date of your makeup products and replace them as needed to maintain skin health.