Yes, hand creams can expire. Like any other skincare product, hand creams have a shelf life, which is typically indicated by the manufacturer on the packaging. The expiration date is important because over time, the ingredients in the hand cream can degrade, making the product less effective or potentially causing skin irritation. Expired hand creams may also become contaminated with bacteria, which can pose a risk to your skin health. It's always a good idea to check the expiration date and replace your hand cream if it has expired.