Yes, you can use Aczone (dapsone) and azelaic acid together as part of your skincare routine. Aczone is a prescription topical medication that primarily targets acne by reducing inflammation and fighting bacteria. Azelaic acid is a naturally occurring compound that has both antibacterial and anti-inflammatory properties, making it effective for treating acne as well as other skin concerns like hyperpigmentation and rosacea.

These two ingredients work through different mechanisms to improve the skin, so using them together can provide complementary benefits. Aczone primarily targets the bacteria associated with acne, while azelaic acid helps to exfoliate the skin, reduce redness, and fade discoloration.

However, it's always a good idea to consult with a dermatologist or healthcare professional before combining any skincare products, especially if they are prescription medications. They can assess your specific skin needs and provide personalized advice on the best way to incorporate these ingredients into your routine.